Application | Comment | Organism |
---|---|---|
drug development | barrier state B1 is a relevant molecular structure to be considered in the design of new inhibitors of the NS3 enzyme. Residues Arg-109, Lys-136, Gly-137, Arg-155 and Asp-79 are responsible for the electrostatic stabilization of B1. The tetra-coordinated intermediate I1, may also be of interest as possible targets for the design of new drugs | Hepacivirus C |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hepacivirus C | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NS5A/5B + H2O | - |
Hepacivirus C | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NS3 protease | - |
Hepacivirus C |