Inhibitors | Comment | Organism | Structure |
---|---|---|---|
fluorescein-L-Asp-D-Glu-L-Leu-L-Ile-L-beta-cyclohexylalanine-L-Cys-L-Pro-L-beta-cyclohexylalanine-L-Asp-L-Leu-NH2 | i.e. PepInh-1, noncleavable decapeptidyl inhibitor | Hepacivirus C |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.051 | - |
o-aminobenzoyl (Abz)-L-Asp-L-Asp-L-Ile-L-Val-L-Pro-L-Cys-L-Ser-L-Met-L-Ser-L-Tyr(3-NO2)-L-Thr-NH2 | pH 7.3, 30°C | Hepacivirus C |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | membrane anchoring of enzyme does not affect substrate/inhibitor recognition | Hepacivirus C | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hepacivirus C | - |
expression in human osteosarcoma cells | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
specific and sensitive assay using an internally quenched fluorogenic substrate | Hepacivirus C |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
o-aminobenzoyl (Abz)-L-Asp-L-Asp-L-Ile-L-Val-L-Pro-L-Cys-L-Ser-L-Met-L-Ser-L-Tyr(3-NO2)-L-Thr-NH2 + H2O | i.e. IQGS-1, internally quenched fluorogenic substrate | Hepacivirus C | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0065 | - |
o-aminobenzoyl (Abz)-L-Asp-L-Asp-L-Ile-L-Val-L-Pro-L-Cys-L-Ser-L-Met-L-Ser-L-Tyr(3-NO2)-L-Thr-NH2 | pH 7.3, 30°C | Hepacivirus C |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000124 | - |
fluorescein-L-Asp-D-Glu-L-Leu-L-Ile-L-beta-cyclohexylalanine-L-Cys-L-Pro-L-beta-cyclohexylalanine-L-Asp-L-Leu-NH2 | pH 7.3, 30°C | Hepacivirus C |