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Literature summary for 3.4.21.98 extracted from

  • Poliakov, A.; Hubatsch, I.; Shuman, C.F.; Stenberg, G.; Danielson, U.H.
    Expression and purification of recombinant full-length NS3 protease-helicase from a new variant of hepatitis C virus (2002), Protein Expr. Purif., 25, 363-371.
    View publication on PubMed
Search for more literature for 3.4.21.98

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Hepacivirus C

Inhibitors

Inhibitors Comment Organism Structure
acetyl-Asp-D-(gamma-carboxyglutamic acid)-Leu-Ile-(beta-cyclohexylalanine)-Cys
-
 Hepacivirus C
acetyl-Asp-Glu-(3,3-diphenylalanine)-Glu-(beta-cyclohexylalanine)-Cys
-
 Hepacivirus C
acetyl-Asp-Glu-(3,3-diphenylalanine)-Ile-(beta-cyclohexylalanine)-Cys
-
 Hepacivirus C
acetyl-Asp-Glu-Leu-Glu-(beta-cyclohexylalanine)-Cys
-
 Hepacivirus C
acetyl-Asp-Glu-Met-Glu-Glu-Cys
-
 Hepacivirus C

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
 x * 70000, SDS-PAGE Hepacivirus C

Organism

Organism UniProt Comment Textmining
Hepacivirus C
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Hepacivirus C

Source Tissue

Source Tissue Comment Organism Textmining

Subunits

Subunits Comment Organism
? x * 70000, SDS-PAGE Hepacivirus C

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000012
-
 acetyl-Asp-D-(gamma-carboxyglutamic acid)-Leu-Ile-(beta-cyclohexylalanine)-Cys pH 7.5, 30°C Hepacivirus C
0.000041
-
 acetyl-Asp-Glu-(3,3-diphenylalanine)-Glu-(beta-cyclohexylalanine)-Cys pH 7.5, 30°C Hepacivirus C
0.00022
-
 acetyl-Asp-Glu-(3,3-diphenylalanine)-Ile-(beta-cyclohexylalanine)-Cys pH 7.5, 30°C Hepacivirus C
0.00036
-
 acetyl-Asp-Glu-Met-Glu-Glu-Cys pH 7.5, 30°C Hepacivirus C
0.00049
-
 acetyl-Asp-Glu-Leu-Glu-(beta-cyclohexylalanine)-Cys pH 7.5, 30°C Hepacivirus C