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Literature summary for 3.4.21.98 extracted from

  • Richer, M.J.; Juliano, L.; Hashimoto, C.; Jean, F.
    Serpin mechanism of hepatitis C virus nonstructural 3 (NS3) protease inhibition: induced fit as a mechanism for narrow specificity (2004), J. Biol. Chem., 279, 10222-10227.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
SP6EVC/S inhibits by slow tight binding mechanism characteristics of serpin molecules, operating as a suicide substrate inhibitor. HCV-Pep4A is required for efficient formation of SDS-stable complex between NS3 protein and SP6EVC/S Hepacivirus C

Organism

Organism UniProt Comment Textmining
Hepacivirus C
-
-
-

Synonyms

Synonyms Comment Organism
nonstructural 3 protease
-
Hepacivirus C
NS3/4A protease
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Hepacivirus C