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Literature summary for 3.4.21.97 extracted from

  • Fernandes, S.; Brignole, E.; Taori, K.; Gibson, W.
    Cytomegalovirus capsid protease: Biological substrates are cleaved more efficiently by full-length enzyme (pUL80a) than by the catalytic domain (Assemblin) (2011), J. Virol., 85, 3526-3534.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information stabilized against self-cleavage by a single point mutation in its cleavage site (IC-assemblin) Cytomegalovirus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
assembly protein precursor of CMV (pAP) + H2O Cytomegalovirus
-
?
-
?
pPR + H2O Cytomegalovirus one substrate used in this study is pPR itself inactivated by replacing its catalytic nucleophile (S132A) ?
-
?

Organism

Organism UniProt Comment Textmining
Cytomegalovirus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
using affinity chromatography purified Cytomegalovirus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
assembly protein precursor of CMV (pAP) + H2O
-
Cytomegalovirus ?
-
?
pPR + H2O one substrate used in this study is pPR itself inactivated by replacing its catalytic nucleophile (S132A) Cytomegalovirus ?
-
?

Synonyms

Synonyms Comment Organism
Assemblin
-
Cytomegalovirus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
additional information
-
assay carried out at room temperature Cytomegalovirus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
assay at Cytomegalovirus