Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.96 extracted from

  • Bruinenberg, P.G.; de Vos, W.M.; Siezen, R.J.
    Prevention of C-terminal autoprocessing of Lactococcus lactis SK11 cell-envelope proteinase by engineering of an essential surface loop (1994), Biochem. J., 302, 957-963.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.96

Cloned(Commentary)

Cloned (Comment) Organism
-
 Lactococcus lactis

Protein Variants

Protein Variants Comment Organism
additional information in strain SK11 the mutagenesis of the loop 205-219 region of the catalytic domain results in inactivation, mostly due to inhibiton of autoprocessing of proenzyme Lactococcus lactis

Localization

Localization Comment Organism GeneOntology No. Textmining
cell envelope
-
 Lactococcus lactis 30313
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
145000
-
 strain SK11, x * 145000, SDS-PAGE Lactococcus lactis
200000
-
 strain SK11, x * 200000, inactive, unprocessed precursor of an active-site mutant Lactococcus lactis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Usp 45 + H2O Lactococcus lactis a secreted 60 kDa protein of Lactococcus lactis ?
-
 ?
Usp 45 + H2O Lactococcus lactis SK11 a secreted 60 kDa protein of Lactococcus lactis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Lactococcus lactis
-
 SK11
-
Lactococcus lactis SK11
-
 SK11
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alphas1-Casein + H2O
-
 Lactococcus lactis Fragments of alphas1-casein
-
 ?
alphas1-Casein + H2O
-
 Lactococcus lactis SK11 Fragments of alphas1-casein
-
 ?
alphas1-Casein fragment 1-23 + H2O
-
 Lactococcus lactis Fragments of alphas1-casein fragment 1-23
-
 ?
alphas1-Casein fragment 1-23 + H2O
-
 Lactococcus lactis SK11 Fragments of alphas1-casein fragment 1-23
-
 ?
beta-Casein + H2O
-
 Lactococcus lactis Fragments of beta-casein
-
 ?
beta-Casein + H2O
-
 Lactococcus lactis SK11 Fragments of beta-casein
-
 ?
Usp 45 + H2O a secreted 60 kDa protein of Lactococcus lactis Lactococcus lactis ?
-
 ?
Usp 45 + H2O a secreted 60 kDa protein of Lactococcus lactis Lactococcus lactis SK11 ?
-
 ?

Subunits

Subunits Comment Organism
? strain SK11, x * 145000, SDS-PAGE Lactococcus lactis
? strain SK11, x * 200000, inactive, unprocessed precursor of an active-site mutant Lactococcus lactis

Synonyms

Synonyms Comment Organism
Lactococcal proteinase PI
-
 Lactococcus lactis