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Literature summary for 3.4.21.94 extracted from
- Pro-protein convertases of subtilisin/kexin family (1994), Methods Enzymol., 244, 175-188.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | processing of precursors that are routed toward secretory granules | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | distribution in tissues | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | cleavage specificity, cleaves precursors both at specific single and pairs of basic residues, not: prorenin, prosomatostatin | Homo sapiens | ? | - |
? | |
| additional information | processing of precursors that are routed toward secretory granules | Homo sapiens | ? | - |
? | |
| Pro-opiomelanocortin + H2O | from mouse and pig | Homo sapiens | Opiomelanocortin + ? | - |
? | |
| prodynorphin + H2O | rat | Homo sapiens | dynorphin + ? | - |
? | |
| prodynorphin + H2O | cleavage at a single Arg residue | Homo sapiens | dynorphin + ? | - |
? | |
| prodynorphin + H2O | at a bond in which P2 is Thr | Homo sapiens | dynorphin + ? | - |
? | |
| Proenkephalin + H2O | human | Homo sapiens | Enkephalin + ? | - |
? | |
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Release 2023.1 (January 2023)
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