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Literature summary for 3.4.21.89 extracted from
- ER type I signal peptidase subunit (LmSPC1) is essential for the survival of Locusta migratoria manilensis and affects moulting, feeding, reproduction and embryonic development (2014), Insect Mol. Biol., 23, 269-285.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Locusta migratoria manilensis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Locusta migratoria manilensis | R9UE57 | catalytic subunit SEC11 | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Spc1 | - |
Locusta migratoria manilensis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | RNAi-mediated knockdown of the catalytic subunit gene results in high mortality. Sixty-nine per cent of dead nymphs died of abnormal moulting, corresponding to decreased activity of moulting fluid protease. Insects in the RNAi group experience a decline in food intake, and a decrease in the secretion of total protein and digestive enzymes from midgut tissues to the midgut lumen. The females produce fewer eggs and eggs with disrupted embryogenesis | Locusta migratoria manilensis |
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Release 2023.1 (January 2023)
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