Literature summary for 3.4.21.88 extracted from

Jochmann, N.; Kurze, A.-K.; Czaja, L.F.; Brinkoff, K.; Brune, I.; Hueser, A.T.; Hansmeier, N.; Puehler, A.; Boronok, I.; Tauch, A.
Genetic makeup of the Corynebacterium glutamicum LexA regulon deduced from comparative transcriptomics and in vitro DNA band shift assays (2009), Microbiology, 155, 1459-1477.

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Cloned(Commentary)

Cloned (Comment)	Organism
wild-type strain ATCC 13032 and mutant strain NJ2114, DNA sequence and genetic structure determination and analysis, and gene expression profiling of the lexA. Detection of 46 potential SOS boxes located upstream of differentially expressed transcription units. Binding of a hexahistidyl-tagged LexA protein to 40 double-stranded oligonucleotides containing the potential SOS boxes. LexA binds not only to SOS boxes in the promoter-operator region of upregulated genes, but also to SOS boxes detected upstream of downregulated genes, overview. Genetic organization of the lexA-divS intergenic region deduced from promoter mapping. LexA expression in Escherichia coli strain BL21(DE3)	Corynebacterium glutamicum

Cloned (Comment)

Organism

wild-type strain ATCC 13032 and mutant strain NJ2114, DNA sequence and genetic structure determination and analysis, and gene expression profiling of the lexA. Detection of 46 potential SOS boxes located upstream of differentially expressed transcription units. Binding of a hexahistidyl-tagged LexA protein to 40 double-stranded oligonucleotides containing the potential SOS boxes. LexA binds not only to SOS boxes in the promoter-operator region of upregulated genes, but also to SOS boxes detected upstream of downregulated genes, overview. Genetic organization of the lexA-divS intergenic region deduced from promoter mapping. LexA expression in Escherichia coli strain BL21(DE3)

Corynebacterium glutamicum

Protein Variants

Protein Variants	Comment	Organism
additional information	deletion of lexA gene of strain ATCC 13032 to create the mutant strain NJ2114, which has an elongated cell morphology and an increased doubling time. Comparison of SOS regulon, the transcriptomes of NJ2114, and a DNA-damage-induced wild-type strain with the wild-type control using DNA microarray hybridization, overview	Corynebacterium glutamicum

Organism

Organism	UniProt	Comment	Textmining
Corynebacterium glutamicum	-	strain ATCC 13032, gene lexA	-

Subunits

Subunits	Comment	Organism
More	LexA protein contains an N-terminal helix-turn-helix motif of the wingedhelix type, amino acid residues 31-96, and a C-terminal LexA/signal peptidase domain, amino acid residues 133-252	Corynebacterium glutamicum

Synonyms

Synonyms	Comment	Organism
Cg2114	-	Corynebacterium glutamicum
LexA	-	Corynebacterium glutamicum
LexA protein	-	Corynebacterium glutamicum