Cloned (Comment) | Organism |
---|---|
LexA repressor is overexpressed using Escherichia coli strain JL652 | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Escherichia coli | LexA repressor coordinately controls about 20 unlinked genes comprising the bacterial SOS response, an inducible DNA repair system, these genes are necessary for functions as diverse as mutagenesis, DNA repair, recombionation, cell division, and prophage induction, SOS response is activated upon autoproteolysis of LexA repressor into its two separate domains | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + H2O | - |
Escherichia coli | DNA-loop + ? | - |
? | |
additional information | LexA repressor coordinately controls about 20 unlinked genes comprising the bacterial SOS response, an inducible DNA repair system, these genes are necessary for functions as diverse as mutagenesis, DNA repair, recombionation, cell division, and prophage induction, SOS response is activated upon autoproteolysis of LexA repressor into its two separate domains | Escherichia coli | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | protein is monomeric in absence of DNA, the operator-bound form of LexA repressor is thought to be a dimer | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
LexA repressor | - |
Escherichia coli |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
20 | - |
autoproteolysis of the protein occurs with a half-life of roughly 2 h at pH 9.5 | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
binding affinity of LexA repressor for operator is greatest near neutral pH | Escherichia coli |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
3.9 | 9.3 | - |
Escherichia coli |