Cloned (Comment) | Organism |
---|---|
expression in Pichia pastoris | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
interleukin IL-1alpha + H2O | Homo sapiens | cleavage after the motif IAND103, no substrate for caspases -1, -3, -4, -5, and -7 | ? | granzyme B-mediated processing of IL-1alpha potently enhances the biological activity | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
interleukin IL-1alpha + H2O | cleavage after the motif IAND103, no substrate for caspases -1, -3, -4, -5, and -7 | Homo sapiens | ? | granzyme B-mediated processing of IL-1alpha potently enhances the biological activity | ? | |
additional information | no substrate: interleukin IL-1beta | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Gzm B | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | granzyme B-mediated processing of IL-1alpha potently enhances the biological activity. Granzyme B does not directly influence inflammatory cytokine production by HeLa or HUVEC cells | Homo sapiens |