Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphocyte | wild-type CD8alpha+ intraepithelial lymphocytes constitutively express granzyme B | Mus musculus | - |
T-lymphocyte | granzyme B and granzyme C expression is detected in CD4+ and CD8+ T cells activated with CD3/CD28 beads or MLRs | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
granzyme B | - |
Mus musculus |
GzmB | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | stimulation of NK cells in vitro with IL-15 induce expression of granzyme C | up |
General Information | Comment | Organism |
---|---|---|
malfunction | knockout GzmB-/- mice which have a small deletion in the granzyme B gene express granzyme C earlier and more abundantly in lymphocytes on a per-cell basis compared to wild-type, suggesting that the deleted 350-bp region in the granzyme B gene is important for the regulation of both granzymes B and granzyme C. Intraepithelial lymphocytes in GzmB-/- knockout mice likewise express granzyme C | Mus musculus |