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Literature summary for 3.4.21.79 extracted from
- Identification of granzyme B-expressing CD-8-positive T cells in lymphocytic inflammatory infiltrate in cutaneous lupus erythematosus and in dermatomyositis (2009), Clin. Exp. Dermatol., 34, 910-914.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | granzyme B GrB labels a subpopulation of effector cells involved in ongoing cytotoxic action should be considered as a specific marker showing the extent of the direct local cytotoxic damage in patients with lupus erythematosus | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| skin | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| granzyme B | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | in patients with lupus erythematosus, a correlation between GrB+ lymphocyte and the presence of discoid lupus erythematosus form is found, but in dermatomyositis, GrB is poorly expressed | Homo sapiens |
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