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BRENDA support

Literature summary for 3.4.21.77 extracted from

  • Catalona, W.J.; Partin, A.W.; Sanda, M.G.; Wei, J.T.; Klee, G.G.; Bangma, C.H.; Slawin, K.M.; Marks, L.S.; Loeb, S.; Broyles, D.L.; Shin, S.S.; Cruz, A.B.; Chan, D.W.; Sokoll, L.J.; Roberts, W.L.; van Schaik, R.H.; Mizrahi, I.A.
    A multicenter study of [-2]pro-prostate specific antigen combined with prostate specific antigen and free prostate specific antigen for prostate cancer detection in the 2.0 to 10.0 ng/ml prostate specific antigen range (2011), J. Urol., 185, 1650-1655.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine evaluation of the use of proPSA, free PSA, and PSA to enhance specificity for detecting overall and high-grade prostate cancer. Study on men in a prospective multi-institutional trial with no history of prostate cancer shows that prostate health index Phi may be useful in prostate cancer screening to reduce unnecessary biopsies in men age over 50 years with PSA values of 2-10 ng/ml and negative digital rectal examination findings, with minimal loss in sensitivity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
prostate
-
Homo sapiens
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serum
-
Homo sapiens
-