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Literature summary for 3.4.21.76 extracted from

  • Pederzoli, M.; Kantari, C.; Gausson, V.; Moriceau, S.; Witko-Sarsat, V.
    Proteinase-3 induces procaspase-3 activation in the absence of apoptosis: potential role of this compartmentalized activation of membrane-associated procaspase-3 in neutrophils (2005), J. Immunol., 174, 6381-6390.
    View publication on PubMed
Search for more literature for 3.4.21.76

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens
-
 Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
S203A inactive Homo sapiens
S203A inactive Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Homo sapiens 5886
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P24158
-
-
Rattus norvegicus Q8K597
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
basophilic leukemia cell line
-
 Rattus norvegicus
-
HMC-1 cell
-
 Homo sapiens
-
neutrophil
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Boc-Ala-Pro-Nva-thiobenzylester + H2O pH 7.5, serine-protease activity of PR3 Homo sapiens ?
-
 ?
Boc-Ala-Pro-Nva-thiobenzylester + H2O pH 7.5, serine-protease activity of PR3 Rattus norvegicus ?
-
 ?
procaspase-3 + H2O
-
 Rattus norvegicus ? in vitro, purified PR3 cleaves procaspase-3 into an active 22 kDa fragment ?
procaspase-3 + H2O 37°C Homo sapiens ? in vitro, purified PR3 cleaves procaspase-3 into an active 22 kDa fragment ?

Synonyms

Synonyms Comment Organism
PR3
-
 Homo sapiens
PR3
-
 Rattus norvegicus
proteinase 3
-
 Homo sapiens
proteinase 3
-
 Rattus norvegicus
Proteinase-3
-
 Homo sapiens
Proteinase-3
-
 Rattus norvegicus