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Literature summary for 3.4.21.76 extracted from
- Proteinase 3: substrate specificity and possible pathogenetic effect of Wegeners granulomatosis autoantibodies (c-ANCA) by dysregulation of the enzyme (1993), Adv. Exp. Med. Biol., 336, 55-60.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alpha1-antitrypsin | - |
Homo sapiens | |
| Eglin c | weak | Homo sapiens |  |
| elafin | - |
Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| azurophil granule | from human polymorphonuclear leukocytes (PMNL) | Homo sapiens | 42582 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
Wegener's granulomatosis | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| polymorphonuclear leukocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Elastin + H2O | - |
Homo sapiens | Hydrolyzed elastin | - |
? | |
| Tert-Butyloxycarbonyl-Ala-Ala-norvaline thiobenzyl ester + H2O | best substrate | Homo sapiens | ? | - |
? | |
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