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Literature summary for 3.4.21.75 extracted from
- Ovarian furin (proprotein convertase subtilisin/kexin type3): expression, localization, and potential role in ovulation in the rat (2010), Biol. Reprod., 83, 147-154.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| furin inhibitor I | - |
Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
female Sprague-Dawley rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| ovarian follicle | - |
Rattus norvegicus | - |
| ovary | expression and regulation of furin in ovarian tissue, injection of equine and human chorionic gondotropin, overview | Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FUR | - |
Rattus norvegicus |
| PACE | - |
Rattus norvegicus |
| PCSK3 | - |
Rattus norvegicus |
| proprotein convertase subtilisin/kexin type3 | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | the enzyme is induced by forskolin and amphiregulin, periovulatory furin expression is also increased by human chorionic gondotropin in follicles, overview | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | furin inhibition leads to a 38% reduction of oocyte release from ovaries, overview | Rattus norvegicus |
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