Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.75 extracted from

  • Kim, J.M.; Jang, S.A.; Yu, B.J.; Sung, B.H.; Cho, J.H.; Kim, S.C.
    High-level expression of an antimicrobial peptide histonin as a natural form by multimerization and furin-mediated cleavage (2008), Appl. Microbiol. Biotechnol., 78, 123-130.
    View publication on PubMed

Application

Application Comment Organism
industry furin may be applied in mass production of a potent antimicrobial peptide histonin as a natural form, whereby overcoming its inherent toxicity and the low yield of production Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
vector pcDNA3-furin expressed in HEK-293 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
histonin + H2O furin releases intact histonin monomers from F4-multimeric histonin (12-mer). Histonin has an RLKR motif at the C-terminus after which furin cleaves specifically Homo sapiens ?
-
?