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Literature summary for 3.4.21.72 extracted from

  • Zhang, A.; Mu, X.; Chen, B.; Han, L.; Chen, H.; Jin, M.
    IgA1 protease contributes to the virulence of Streptococcus suis (2011), Vet. Microbiol., 148, 436-439.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information construction of an isogenic iga mutant DELTAiga by allelic replacement, which shows significantly decreased lethality to pigs. Removal of gene iga contributes to weakening the ability of Streptoccocus suis in breaking through the mucosa barrier of a host and its inability to invade the pigs Streptococcus suis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
porcine IgA1 + H2O Streptococcus suis
-
?
-
?
porcine IgA1 + H2O Streptococcus suis 05ZYS
-
?
-
?

Organism

Organism UniProt Comment Textmining
Streptococcus suis
-
serotype 2, isolated from pig brain, gene iga
-
Streptococcus suis 05ZYS
-
serotype 2, isolated from pig brain, gene iga
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
porcine IgA1 + H2O
-
Streptococcus suis ?
-
?
porcine IgA1 + H2O
-
Streptococcus suis 05ZYS ?
-
?

Synonyms

Synonyms Comment Organism
IgA1 protease
-
Streptococcus suis

General Information

General Information Comment Organism
physiological function IgA1 protease is a virulence factor of the pathogenic bacterium required for its pathogenesis Streptococcus suis