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Literature summary for 3.4.21.7 extracted from

  • Castellino, F.J.; Sodetz, J.M.
    Rabbit plasminogen and plasmin isozymes (1976), Methods Enzymol., 45, 273-286.
    View publication on PubMed
Search for more literature for 3.4.21.7

Inhibitors

Inhibitors Comment Organism Structure
6-aminohexanoic acid weak, competitive Oryctolagus cuniculus
benzamidine
-
 Oryctolagus cuniculus
DFP
-
 Oryctolagus cuniculus
Pancreatic trypsin inhibitor
-
 Oryctolagus cuniculus
PMSF
-
 Oryctolagus cuniculus
Soybean trypsin inhibitor
-
 Oryctolagus cuniculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.3
-
 tosyl-Arg methyl ester enzyme form F-1 Oryctolagus cuniculus
7
-
 tosyl-Arg methyl ester enzyme form F-2 Oryctolagus cuniculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
82000 84000 enzyme inactivated with diisopropyl fluorophosphate, enzyme form F-2, high speed analytical ultracentrifugation Oryctolagus cuniculus
83000 86000 enzyme inactivated with diisopropyl fluorophosphate, enzyme form F-1, high speed analytical ultracentrifugation Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
enzyme form F-1 and enzyme form F-2 Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Tosyl-Arg methyl ester + H2O
-
 Oryctolagus cuniculus ?
-
 ?

Subunits

Subunits Comment Organism
monomer the enzyme consists of a 24000-26000 Da light chain and a 60000-63000 Da heavy chain, enzyme form F-1, high speed analytical ultracentrifugation in 6 M guanidine HCl Oryctolagus cuniculus
monomer the enzyme consists of a 24000-26000 Da light chain and a 59000-62000 Da heavy chain, enzyme form F-2, high speed analytical ultracentrifugation in 6 M guanidine HCl Oryctolagus cuniculus