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Literature summary for 3.4.21.69 extracted from

  • Puig, F.; Fuster, G.; Adda, M.; Blanch, L.; Farre, R.; Navajas, D.; Artigas, A.
    Barrier-protective effects of activated protein C in human alveolar epithelial cells (2013), PLoS ONE, 8, e56965.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
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Homo sapiens
-
alveolar epithelial cell
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Homo sapiens
-

Synonyms

Synonyms Comment Organism
Activated protein C
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Homo sapiens
APC
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Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme significantly reduced thrombin-induced cell monolayer permeability, cell stiffening, and cell contraction. The enzyme reduces the disruption of barrier integrity induced by thrombin, thus contributing to alveolar epithelial barrier protection, overview Homo sapiens