Literature summary for 3.4.21.69 extracted from

Kowalska, M.A.; Zhao, G.; Zhai, L.; David, G.; Marcus, S.; Krishnaswamy, S.; Poncz, M.
Modulation of protein C activation by histones, platelet factor 4, and heparinoids: new insights into activated protein C formation (2014), Arterioscler. Thromb. Vasc. Biol., 34, 120-126.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
proteolytic modification	modulation of protein C activation by histones, platelet factor 4, and heparinoids, overview. The 2-O, 3-O desulfated heparin affects activated protein C generation in the presence of histones and platelet factor 4, histones alone enhance protein C activation, while the enhancement is inhibited by platelet factor 4 addition	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S2366 + H2O	a chromogenic substrate	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
Activated protein C	-	Homo sapiens
APC	-	Homo sapiens

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Release 2023.1 (January 2023)