Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | the activated enzyme induces cytsolic Ca2+ signals, mechanism | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the activated enzyme induces signal transduction in an endothelial protein C receptor- or PAR1-dependent manner involved in apoptosis, microcirculation, and vascular permeability, the activated enzyme plays an important role in sepsis, but does not protect against sepsis, effects of long time treatment, overview, the activated enzyme induces expression of monocyte chemoattractant protein-1, MCP-1, in endothelial cells, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
endothelium | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the activated enzyme induces signal transduction in an endothelial protein C receptor- or PAR1-dependent manner involved in apoptosis, microcirculation, and vascular permeability, the activated enzyme plays an important role in sepsis, but does not protect against sepsis, effects of long time treatment, overview, the activated enzyme induces expression of monocyte chemoattractant protein-1, MCP-1, in endothelial cells, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
anticoagulant activated protein C | - |
Homo sapiens |