Literature summary for 3.4.21.69 extracted from

Gale, A.J.; Griffin, J.H.
Characterization of a thrombomodulin binding site on protein C and its comparison to an activated protein C binding site for factor Va (2004), Proteins, 54, 433-441.

Search for more literature for 3.4.21.69

Protein Variants

Protein Variants	Comment	Organism
K191A	Km- and kcat-value similar to wild-type, minor contribution to interaction with thrombin-thrombomodulin	Homo sapiens
K192A	Km- and kcat-value similar to wild-type, major contribution to interaction with thrombin-thrombomodulin	Homo sapiens
K217A	Km- and kcat-value similar to wild-type, minor contribution to interaction with thrombin-thrombomodulin	Homo sapiens
K218A	Km- and kcat-value similar to wild-type, minor contribution to interaction with thrombin-thrombomodulin	Homo sapiens
R229A	Km- and kcat-value similar to wild-type, major contribution to interaction with thrombin-thrombomodulin	Homo sapiens
R230A	Km- and kcat-value similar to wild-type, major contribution to interaction with thrombin-thrombomodulin	Homo sapiens
R312A	Km- and kcat-value similar to wild-type, minor contribution to interaction with thrombin-thrombomodulin	Homo sapiens
S190A	Km- and kcat-value similar to wild-type, minor contribution to interaction with thrombin-thrombomodulin	Homo sapiens
W231A	Km- and kcat-value similar to wild-type, minor contribution to interaction with thrombin-thrombomodulin	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	recombinant protein	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

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Release 2023.1 (January 2023)