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Literature summary for 3.4.21.69 extracted from
- Altered inactivation pathway of factor Va by activated protein C in the presence of heparin (2004), Eur. J. Biochem., 271, 2724-2736.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| heparin | heparin forms a complex with enzyme and inhibits optimal docking at Arg506 of substrate factor Va, instead promoting association between factor Va and enzyme at position Arg306 | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
recombinant enzyme | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Factor Va + H2O | hydrolysis at Arg506 | Homo sapiens | ? | - |
? | |
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Release 2023.1 (January 2023)
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