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Literature summary for 3.4.21.68 extracted from
- Regulation of tissue plasminogen activator activity by cells. Domains responsible for binding and mechanism of stimulation (1999), J. Biol. Chem., 274, 12414-12422.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| plasminogen + H2O | Homo sapiens | - |
plasmin + ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| plasminogen + H2O | - |
Homo sapiens | plasmin + ? | - |
? | |
| Val-Leu-Lys-p-nitroanilide + H2O | i.e. S-2251 | Homo sapiens | p-nitroaniline + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Tissue plasminogen activator | - |
Homo sapiens |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.06 | - |
plasminogen | pH 7.4, 37°C | Homo sapiens |
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