Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Fibrin | enhances activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-1-Proteinase inhibitor | - |
Homo sapiens | |
alpha-2-Antiplasmin | - |
Homo sapiens | |
alpha-2-Macroglobulin | - |
Homo sapiens | |
C1-inhibitor | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
70000 | - |
x * 70000, human, SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
plasminogen + H2O | Homo sapiens | responsible for practically all vascular fibrinolysis through activation of plasminogen | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | glycosylated at three of the four potential glycosylation sites | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
saliva | - |
Homo sapiens | - |
seminal plasma | - |
Homo sapiens | - |
tear | - |
Homo sapiens | - |
urine | - |
Homo sapiens | - |
uterus | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
plasminogen + H2O | cleavage of an Arg-Val bond near the carboxy-terminal end | Homo sapiens | plasmin + ? | Glu-plasmin consists of two polypeptides, MW 25000 and 65000, linked together by two disulfide bonds | ? | |
plasminogen + H2O | Glu-plasminogen is the native form of human plasminogen | Homo sapiens | plasmin + ? | Glu-plasmin consists of two polypeptides, MW 25000 and 65000, linked together by two disulfide bonds | ? | |
plasminogen + H2O | responsible for practically all vascular fibrinolysis through activation of plasminogen | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 70000, human, SDS-PAGE | Homo sapiens |
More | the single-chain PA may occur in inactive and active forms | Homo sapiens |