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Literature summary for 3.4.21.64 extracted from

  • Kore, A.R.; Shanmugasundaram, M.; Hoang, Q.; Kuo, M.; Chapman, L.M.; Chen, H.H.
    Synthesis and application of MeOSuc-Ala-Ala-Pro-Phe-CH2Cl as potent proteinase K inhibitor (2009), Bioorg. Med. Chem. Lett., 19, 1296-1300.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
computer modeling studies indicates the presence of a small binding pocket in the vicinity of the proteinase K active site, which may be filled by the aromatic phenylalanine moiety Parengyodontium album

Inhibitors

Inhibitors Comment Organism Structure
MeOSuc-Ala-Ala-Pro-Phe-CH2Cl examination of inhibitory activity using a real-time reverse transcription-polymerase chain reaction assay in the presence of proteinase K. The AAPF inhibitor at a concentration of 0.05 mM allows a signal to be obtained for exogenous target Xeno RNA at 30 cycles Parengyodontium album

Organism

Organism UniProt Comment Textmining
Parengyodontium album P06873
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