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Literature summary for 3.4.21.61 extracted from
- Serum proprotein convertase subtilisin kexin type 9 is correlated directly with serum LDL cholesterol (2007), Clin. Chem., 53, 1814-1819.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | circulating concentrations of human PCSK9 are directly correlated with LDL and total cholesterol concentrations. PCSK9 is likely not associated with specific lipoprotein particles. Assay providing a means to tailor PCSK9-inhibitor therapy to patients most likely to respond to and benefit from pharmacologic inhibition of PCSK9 | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpressed in HEK-293 cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| by Ni-nitriloacetic acid and size-exclusion chromatography, more than 95% pure | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| serum | concentrations of PCSK9 in serum vary considerably from person to person | Homo sapiens | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -70°C | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PCSK9 | - |
Homo sapiens |
| proprotein convertase subtilisin kexin type 9 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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