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Literature summary for 3.4.21.6 extracted from
- Lyso-sulfatide binds factor Xa and inhibits thrombin generation by the prothrombinase complex (2015), PLoS ONE, 10, e0135025 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-2765 + H2O | - |
Homo sapiens | Z-D-Arg-Gly-L-Arg + 4-nitroaniline | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| factor Xa | - |
Homo sapiens |
| FXa | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | sphingolipids, including lysosulfatide and some of its analogs like N-acetyl sulfatide, psychosine, gluco-psychosine, lyso-sphingomyelin or sulfatide, may down-regulate enzyme activity without inhibiting the enzyme's active site. Lysosulfatide is an anticoagulant lipid that inhibits the enzyme when it is bound to either phospholipids or to factor Va | down |
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