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Literature summary for 3.4.21.6 extracted from

  • Gera, O.; Bushi, D.; Ben Shimon, M.; Artan-Furman, A.; Harnof, S.; Maggio, N.; Dori, A.; Chapman, J.; Shavit-Stein, E.
    Local regulation of thrombin activity by factor Xa in peripheral nerve Schwann cells (2018), Neuroscience, 371, 445-454 .
    View publication on PubMed
Search for more literature for 3.4.21.6

Inhibitors

Inhibitors Comment Organism Structure
apixaban highly selective inhibitor Homo sapiens
apixaban highly selective inhibitor Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
prothrombin + H2O Mus musculus
-
 thrombin + ?
-
 ?
prothrombin + H2O Homo sapiens
-
 thrombin + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neurilemoma cell
-
 Homo sapiens
-
sciatic nerve
-
 Mus musculus
-
STS-26T cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Boc-L-Asp(OBzl)-L-Pro-L-Arg-7-amido-4-methylcoumarin + H2O I-1560 Mus musculus Boc-L-Asp(OBzl)-L-Pro-L-Arg + 7-amino-4-methylcoumarin
-
 ?
Boc-L-Asp(OBzl)-L-Pro-L-Arg-7-amido-4-methylcoumarin + H2O I-1560 Homo sapiens Boc-L-Asp(OBzl)-L-Pro-L-Arg + 7-amino-4-methylcoumarin
-
 ?
prothrombin + H2O
-
 Mus musculus thrombin + ?
-
 ?
prothrombin + H2O
-
 Homo sapiens thrombin + ?
-
 ?

Subunits

Subunits Comment Organism
? x * 60000, SDS-PAGE Mus musculus
? x * 60000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
factor Xa
-
 Mus musculus
factor Xa
-
 Homo sapiens

Expression

Organism Comment Expression
Mus musculus enzyme protein levels increase 1 h after injury of the peripheral nerve and then decrease significantly at 1 and 2 days following injury up