Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | coagulation factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation through induction of myosin light chain phosphorylation and LIMK1 activation, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | coagulation factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation through induction of myosin light chain phosphorylation and LIMK1 activation, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
factor Xa | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | factor Xa plays a role in blood coagulation. And FXa also plays a key role in cell migration, and is involved in a mechanism of PAR-1-mediated inhibition of migration via Rho and Src dependent pathways | Homo sapiens |