Inhibitors | Comment | Organism | Structure |
---|---|---|---|
apixaban | i.e. BMS-562247, a small molecule able to inhibit in a selective and reversible manner the active site of both free and prothrombinase-bound factor Xa, requires oraladministration, bleeding rates of 0.69% | Homo sapiens | |
DX9065a | requires system administration | Homo sapiens | |
LY517717 | a direct factor Xa inhibitor, requires oraladministration, with an oral bioavailability of 25-82%. LY517717 is apparently primarily cleared via a gastrointestinal route | Homo sapiens | |
additional information | clinical studies, efficacy and safety of factor Xa inhibitors, overview | Homo sapiens | |
otamixaban | requires system administration | Homo sapiens | |
rivaroxaban | i.e. BAY 59-7939, requires oraladministration. It is absorbed in the gastrointestinal tract, is primarily excreted by the kidneys, and has a bioavailability of more than 80%, and bleeding rates of 4.3-10.2% | Homo sapiens | |
YM150 | a direct inhibitor of factor Xa, requires oraladministration,bleeding rate is 11.8-23.5% | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
factor Xa | - |
Homo sapiens |