Literature summary for 3.4.21.6 extracted from

Hirbawi, J.; Bukys, M.A.; Barhoover, M.A.; Erdogan, E.; Kalafatis, M.
Role of the acidic hirudin-like COOH-terminal amino acid region of factor Va heavy chain in the enhanced function of prothrombinase (2008), Biochemistry, 47, 7963-7974.

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Protein Variants

Protein Variants	Comment	Organism
additional information	mutation of factor Va in the prothrombinase enzyme complex consisting of factor Xa and factor Va. The C-terminal region of factor Va heavy chain is crucial for coordinated prothrombin activation by prothrombinase	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	prothrombinase, enzyme complex consisting of factor Xa and factor Va, assembled in a calcium-dependent manner on the surface of phospholipid membranes	-

Subunits

Subunits	Comment	Organism
More	the C-terminal region of factor Va heavy chain is crucial for coordinated prothrombin activation by prothrombinase, an enzyme complex consisting of factor Xa and factor Va	Homo sapiens

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Release 2023.1 (January 2023)