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Literature summary for 3.4.21.6 extracted from

  • Studelska, D.R.; McDowell, L.M.; Adler, M.; O'Connor, R.D.; Mehta, A.K.; Guilford, W.J.; Dallas, J.L.; Arnaiz, D.; Light, D.R.; Schaefer, J.
    Conformation of a bound inhibitor of blood coagulant factor Xa (2003), Biochemistry, 42, 7942-7949.
    View publication on PubMed
Search for more literature for 3.4.21.6

Inhibitors

Inhibitors Comment Organism Structure
ZK-816042 CI-1031, 183305-24-0, amidine-imidazole inhibitor, inhibitor conformation and binding mode to the enzyme is investigated by NMR structure determination of the lyophilized enzyme-inhibitor complex formed in presence of stabilizing excipients Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P00742
-
-

Reaction

Reaction Comment Organism Reaction ID
selective cleavage of Arg-/-Thr and then Arg-/-Ile bonds in prothrombin to form thrombin scutelarin has similar specificity Homo sapiens
a

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
blood coagulation factor Xa
-
 Homo sapiens
factor Xa
-
 Homo sapiens
FXa
-
 Homo sapiens
More the enzyme belongs to the peptidase family S1, i.e. trypsin family Homo sapiens