Application | Comment | Organism |
---|---|---|
medicine | increased tryptase concentrations are a risk marker for the severity of reactions to Hymenoptera stings or venom immunotherapy | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | during the cell death process, tryptase relocalizes from granules into the cytosol and nucleus | Mus musculus | 5829 | - |
nucleus | during the cell death process, tryptase relocalizes from granules into the cytosol and nucleus | Mus musculus | 5634 | - |
secretory granule | - |
Mus musculus | 30141 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
35000 | - |
x * 35000, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
histone 2B + H2O | Mus musculus | - |
? | - |
? | |
histone 3 + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mast cell | - |
Mus musculus | - |
serum | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
histone 2B + H2O | - |
Mus musculus | ? | - |
? | |
histone 3 + H2O | - |
Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 35000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
mast cell protease 6 | - |
Mus musculus |
Mast cell tryptase | - |
Mus musculus |
Mast cell tryptase | - |
Homo sapiens |
MCP-6 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | serum tryptase levels are positively associated with beekeeping activities, Hymenoptera venom allergy, age, and male sex | up |
General Information | Comment | Organism |
---|---|---|
malfunction | tryptase deficiency results in defective proteolytic modification of core histones | Mus musculus |