Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-interleukin-6 + H2O | Rattus norvegicus | - |
interleukin-6 + ? | - |
? | |
pro-nuclear factor-kappa B + H2O | Rattus norvegicus | - |
nuclear factor-kappa B + ? | - |
? | |
pro-tissue necrosis factor + H2O | Rattus norvegicus | - |
tissue necrosis factor + ? | - |
? | |
protease-activated receptor 2 + H2O | Rattus norvegicus | - |
fibrin + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mast cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-interleukin-6 + H2O | - |
Rattus norvegicus | interleukin-6 + ? | - |
? | |
pro-nuclear factor-kappa B + H2O | - |
Rattus norvegicus | nuclear factor-kappa B + ? | - |
? | |
pro-tissue necrosis factor + H2O | - |
Rattus norvegicus | tissue necrosis factor + ? | - |
? | |
protease-activated receptor 2 + H2O | - |
Rattus norvegicus | fibrin + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Mast cell tryptase | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | mast cell tryptase induces microglia activation via protease-activated receptor 2-mitogen-activated protein kinase-nuclear factor kappa B signaling pathway, which will contribute to the development of microglia-mediated inflammation in brain | Rattus norvegicus |