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Literature summary for 3.4.21.59 extracted from

  • Li, Q.; Jie, Y.; Wang, C.; Zhang, Y.; Guo, H.; Pan, Z.
    Tryptase compromises corneal epithelial barrier function (2014), Cell Biochem. Funct., 32, 183-187.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
proteinase-activated receptor 2 + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
corneal epithelial cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
proteinase-activated receptor 2 + H2O
-
Homo sapiens ?
-
?

General Information

General Information Comment Organism
physiological function tryptase can increase the expression of matrix metalloproteinase 9 by activation of proteinase-activated receptor 2 in corneal epithelial cells and compromise the epithelial barrier Homo sapiens