Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.59 extracted from

  • Erba, F.; Fiorucci, L.; Sommerhoff, C.P.; Coletta, M.; Ascoli, F.
    Kinetic and thermodynamic analysis of leech-derived tryptase inhibitor interaction with bovine tryptase and bovine trypsin (2000), Biol. Chem., 381, 1117-1122.
    View publication on PubMed
Search for more literature for 3.4.21.59

Inhibitors

Inhibitors Comment Organism Structure
Bovine pancreatic trypsin inhibitor
-
 Bos taurus
LDTI non-competitive inhibitor, derived from Hirudo medicinalis Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.043
-
 t-butyloxycarbonyl-Phe-Ser-Arg-4-methyl-coumarin 7-amide pH 8.0, 30°C Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
secretory granule
-
 Bos taurus 30141
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
360000
-
-
 Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 bovine
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
t-butyloxycarbonyl-Phe-Ser-Arg-4-methyl-coumarin 7-amide + H2O
-
 Bos taurus ?
-
 ?

Subunits

Subunits Comment Organism
oligomer 10 * 35000-38000 Bos taurus

Synonyms

Synonyms Comment Organism
BLCT
-
 Bos taurus
bovine liver capsule tryptase
-
 Bos taurus
tryptase
-
 Bos taurus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
7
-
 t-butyloxycarbonyl-Phe-Ser-Arg-4-methyl-coumarin 7-amide pH 8.0, 30°C Bos taurus