Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
mitochondrion | - |
Mus musculus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P36776 | - |
- |
Mus musculus | Q8CGK3 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | wild-type and HtrA2 knock-down HEK293T cells | Homo sapiens | - |
MEF cell | HtrA2-/- mouse embryonic fibroblast cells | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
LON protease 1 | - |
Homo sapiens |
LON protease 1 | - |
Mus musculus |
LONP1 | - |
Homo sapiens |
LONP1 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme expression in reguated by HtrA2 serine protease, Lon1 protease is overexpressed in HtrA2-deficient cells, phenotype, overview. HtrA2 regulates mitochondrial proteins through its serine protease activity | Homo sapiens |
physiological function | the enzyme expression in reguated by HtrA2 serine protease, Lon1 protease is overexpressed in HtrA2-deficient cells, phenotype, overview. HtrA2 regulates mitochondrial proteins through its serine protease activity | Mus musculus |