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Literature summary for 3.4.21.53 extracted from

  • Goo, H.G.; Rhim, H.; Kang, S.
    HtrA2/Omi influences the stability of LON protease 1 and prohibitin, proteins involved in mitochondrial homeostasis (2014), Exp. Cell Res., 328, 456-465.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
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mitochondrion
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Mus musculus 5739
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Organism

Organism UniProt Comment Textmining
Homo sapiens P36776
-
-
Mus musculus Q8CGK3
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell wild-type and HtrA2 knock-down HEK293T cells Homo sapiens
-
MEF cell HtrA2-/- mouse embryonic fibroblast cells Mus musculus
-

Synonyms

Synonyms Comment Organism
LON protease 1
-
Homo sapiens
LON protease 1
-
Mus musculus
LONP1
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Homo sapiens
LONP1
-
Mus musculus

General Information

General Information Comment Organism
physiological function the enzyme expression in reguated by HtrA2 serine protease, Lon1 protease is overexpressed in HtrA2-deficient cells, phenotype, overview. HtrA2 regulates mitochondrial proteins through its serine protease activity Homo sapiens
physiological function the enzyme expression in reguated by HtrA2 serine protease, Lon1 protease is overexpressed in HtrA2-deficient cells, phenotype, overview. HtrA2 regulates mitochondrial proteins through its serine protease activity Mus musculus