Literature summary for 3.4.21.53 extracted from

Rudyak, S.G.; Brenowitz, M.; Shrader, T.E.
Mg2+-linked oligomerization modulates the catalytic activity of the Lon (La) protease from Mycobacterium smegmatis (2001), Biochemistry, 40, 9317-9323.

Search for more literature for 3.4.21.53

Activating Compound

Activating Compound	Comment	Organism	Structure
alpha-casein	activates the enzyme	Mycolicibacterium smegmatis
additional information	stimulated by unfolded protein and supported by nonhydrolyzed nucleotide analogs>	Mycolicibacterium smegmatis

Cloned(Commentary)

Cloned (Comment)	Organism
wild-type and S675A mutant expressed in Escherichia coli SGR9	Mycolicibacterium smegmatis

Protein Variants

Protein Variants	Comment	Organism
S675A	constructed mutation of the active site region	Mycolicibacterium smegmatis

Inhibitors

Inhibitors	Comment	Organism	Structure
Urea	-	Mycolicibacterium smegmatis

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	activation, Mg2+ linked oligomerization modulates the catalytic activity	Mycolicibacterium smegmatis

Organism

Organism	UniProt	Comment	Textmining
Mycolicibacterium smegmatis	-	-	-

Subunits

Subunits	Comment	Organism
hexamer	-	Mycolicibacterium smegmatis
oligomer	-	Mycolicibacterium smegmatis

Synonyms

Synonyms	Comment	Organism
lon (la) protease	-	Mycolicibacterium smegmatis
lon protease	-	Mycolicibacterium smegmatis

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Mycolicibacterium smegmatis

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Release 2023.1 (January 2023)