Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | stimulated by unfolded protein and supported by nonhydrolyzed nucleotide analogs | Mycolicibacterium smegmatis |
Cloned (Comment) | Organism |
---|---|
cloned and expressed in Escherichia coli MC1061 | Mycolicibacterium smegmatis |
Protein Variants | Comment | Organism |
---|---|---|
S675A | constructed mutation of the active site region | Mycolicibacterium smegmatis |
S675C | constructed mutation of the active site region | Mycolicibacterium smegmatis |
S675T | constructed mutation of the active site region | Mycolicibacterium smegmatis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
87000 | - |
4 * 87000, homotetramer | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
RcsA + H2O | Escherichia coli | protein degradation mediates the turnover of damaged proteins | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Mycolicibacterium smegmatis | - |
ATCC 607 | - |
Purification (Comment) | Organism |
---|---|
- |
Mycolicibacterium smegmatis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gln-Ala-Ala-Phe-p-nitroanilide + H2O | preferred substrate | Mycolicibacterium smegmatis | ? | - |
? | |
additional information | succinyl-Leu-Leu-Val-Tyr-4-methylcoumarin-7-amide is not cleaved | Mycolicibacterium smegmatis | ? | - |
? | |
RcsA + H2O | - |
Escherichia coli | ? | - |
? | |
RcsA + H2O | - |
Mycolicibacterium smegmatis | ? | - |
? | |
RcsA + H2O | protein degradation mediates the turnover of damaged proteins | Escherichia coli | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 87000, homotetramer | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
lon protease | - |
Escherichia coli |
lon protease | - |
Mycolicibacterium smegmatis |
Ms-Lon | - |
Mycolicibacterium smegmatis |