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Literature summary for 3.4.21.5 extracted from

  • Jhoti, H.; Cleasby, A.; Reid, S.; Thomas, P.J.; Weir, M.; Wonacott, A.
    Crystal structures of thombin complexed to a novel series of synthetic inhibitors containing a 5,5-trans lactone template (1999), Biochemistry, 38, 7969-7977.
    View publication on PubMed
Search for more literature for 3.4.21.5

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of thrombin complexed to a novel series of synthetic inhibitors containing a 5,5'-trans-lactone template Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
GR157368 5-(2-oxo-hexahydro-cyclopenta[b]furna-3-yl)-pentanamide Homo sapiens
GR166081 5-[5-(4-hydroxy-phenyl)-2-oxo-3,3a,8,8a,tetrahydro-2H-indeno[2,1-b]furan-3-yl]-pentanamidine Homo sapiens
GR167088 5-[5-(4-methoxy-phenyl)-2-oxo-3,3a,8,8a-tetrahydro-2H-indeno[2,1-b]furan-3-yl]-pentanamide Homo sapiens
GR179849 4-[3-(4-carbamidoyl-butyl)-2-oxo-1,2,3,3a,8,8a-hexahydro-cyclopenta[a]inden-5-yl]-N,N-diethylbenzamide Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification zymogen: prothrombin Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens