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BRENDA support

Literature summary for 3.4.21.5 extracted from

  • Cuerrier, C.M.; Gagner, A.; Lebel, R.; Gobeil, F.; Grandbois, M.
    Effect of thrombin and bradykinin on endothelial cell mechanical properties monitored through membrane deformation (2009), J. Mol. Recognit., 22, 389-396.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
fibrinogen + H2O Homo sapiens
-
fibrin + fibrinopeptide A + fibrinopeptide B
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fibrinogen + H2O
-
Homo sapiens fibrin + fibrinopeptide A + fibrinopeptide B
-
?

General Information

General Information Comment Organism
physiological function HUVEC cells stimulated with thrombin (10 nM) exhibit an increased amount of actin filaments (show increased cell stiffness) when compared to unstimulated cells Homo sapiens