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Literature summary for 3.4.21.5 extracted from
- Thrombin activation of proteinase-activated receptor 1 potentiates the myofilament Ca2+ sensitivity and induces vasoconstriction in porcine pulmonary arteries (2010), Br. J. Pharmacol., 159, 919-927.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood plasma | - |
Bos taurus | - |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | thrombin activation of proteinase-activated receptor 1 potentiates the myofilament Ca2+ sensitivity and induces vasoconstriction in porcine pulmonary arteries, the contractile effect of thrombin is abolished by either 4-aminidophenyl methane-sulfonyl fluoride or the proteinase-activated receptor 1 antagonist SCH79797, while it is mimicked by proteinase-activated receptor 1-activating peptide but not proteinase-activated receptor 4-activating peptide | Bos taurus |
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Release 2023.1 (January 2023)
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