Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
monocyte | - |
Homo sapiens | - |
General Information | Comment | Organism |
---|---|---|
physiological function | thrombin stimulation induces matrix metalloproteinase-9 secretion of monocytes dose- and time-dependently (0-8 units/ml thrombin), inhibition of thrombin-induced matrix metalloproteinase-9 secretion by either MEK inhibitor or p38 kinase inhibitor reveals that the thrombin effect is mediated by both ERK1/2 and p38 pathways | Homo sapiens |