Literature summary for 3.4.21.5 extracted from

Hosokawa, K.; Ohnishi, T.; Kawakami, A.; Wakabayashi, S.; Koide, T.
Chemically modified thrombin and anhydrothrombin that differentiate macromolecular substrates of thrombin (2005), J. Thromb. Haemost., 3, 2703-2711.

Search for more literature for 3.4.21.5

Protein Variants

Protein Variants	Comment	Organism
additional information	chemical modification of carboxyl groups by glycine ethyl ester. Modified enzyme induces platelet aggregation through the activation of PAR1, and modified anhydrothrombin inhibits this process completely. Neither modified anhydrothrombin nor modified thrombin inhibit thrombin-induced platelet aggregation	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	thrombin and anhydrothrombin chemically modified by glycine ethyl ester	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

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Release 2023.1 (January 2023)