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Literature summary for 3.4.21.45 extracted from

  • Davis III, A.E.; Alper, C.A.
    Factor I (C3b inactivator) the complement regulatory protease (1984), Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. ), 5, 553-558.
No PubMed abstract available
Search for more literature for 3.4.21.45

Activating Compound

Activating Compound Comment Organism Structure
C4-binding protein required for hydrolysis of C4b Cavia porcellus
C4-binding protein required for hydrolysis of C4b Rattus norvegicus
factor H required for hydrolysis of C3b Cavia porcellus
factor H required for hydrolysis of C3b Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C3b + H2O Cavia porcellus enzyme is involved in the regulation of complement activation, it catalyzes the limited proteolysis of the alpha-chains of complement component C4b and complement component C4b ?
-
 ?
complement component C3b + H2O Rattus norvegicus enzyme is involved in the regulation of complement activation, it catalyzes the limited proteolysis of the alpha-chains of complement component C4b and complement component C4b ?
-
 ?
complement component C4b + H2O Cavia porcellus enzyme is involved in the regulation of complement activation, it catalyzes the limited proteolysis of the alpha chains of complement component C4b and C4b ?
-
 ?
complement component C4b + H2O Rattus norvegicus enzyme is involved in the regulation of complement activation, it catalyzes the limited proteolysis of the alpha chains of complement component C4b and C4b ?
-
 ?

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Rattus norvegicus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification glycoprotein Cavia porcellus
side-chain modification glycoprotein Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Cavia porcellus
-
serum
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C3b + H2O
-
 Cavia porcellus complement component C3c + ?
-
 ?
complement component C3b + H2O
-
 Rattus norvegicus complement component C3c + ?
-
 ?
complement component C3b + H2O enzyme is involved in the regulation of complement activation, it catalyzes the limited proteolysis of the alpha-chains of complement component C4b and complement component C4b Cavia porcellus ?
-
 ?
complement component C3b + H2O enzyme is involved in the regulation of complement activation, it catalyzes the limited proteolysis of the alpha-chains of complement component C4b and complement component C4b Rattus norvegicus ?
-
 ?
complement component C4b + H2O
-
 Cavia porcellus complement component C4c + C4d
-
 ?
complement component C4b + H2O
-
 Rattus norvegicus complement component C4c + C4d
-
 ?
complement component C4b + H2O enzyme is involved in the regulation of complement activation, it catalyzes the limited proteolysis of the alpha chains of complement component C4b and C4b Cavia porcellus ?
-
 ?
complement component C4b + H2O enzyme is involved in the regulation of complement activation, it catalyzes the limited proteolysis of the alpha chains of complement component C4b and C4b Rattus norvegicus ?
-
 ?