Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
C5 convertase | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | neither the classical nor the alternative complement pathways are required for disease development of experimental cerebral malaria. C3-/- mice develop severe experimental cerebral malaria through activation of C5 independent of complement C5 convertases by terminal pathway activation. C5 is activated in experimental cerebral malaria through the extrinsic protease pathway, overview. C5-/- mice are highly resistant to experimental cerebral malaria | Mus musculus |