Literature summary for 3.4.21.42 extracted from

Kam, C.M.; Oglesby, T.J.; Pangburn, M.K.; Volanakis, J.E.; Powers, J.C.
Substituted isocoumarins as inhibitors of complement serine proteases (1992), J. Immunol., 149, 163-168.

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Inhibitors

Inhibitors	Comment	Organism	Structure
3,4-dichloroisocoumarin	-	Homo sapiens
4-chloro-3-(3-isothiureidopropoxy)isocoumarin	best inhibitor among substituted isocoumarins	Homo sapiens
4-chloro-3-ethoxy-7-guanidinoisocoumarin	-	Homo sapiens
4-chloro-7-guanidino-3-(2-phenylethoxy)isocoumarin	-	Homo sapiens
4-chloro-7-guanidino-3-methoxyisocoumarin	-	Homo sapiens
7-amino-4-chloro-3-(3-isothiureidopropoxy)isocoumarin	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)